Is the era of medical missions indeed over? The answer to this is both Yes and No. The old paradigm of medical missions is over and should have disappeared a decade or more ago. On the other hand, the challenges, opportunities, and responsibilities facing Christian health ministries are greater than ever. Furthermore, the mandate Christ gave to his disciples to heal the sick has not changed. Obedience to this mandate in the twenty- first century will require new paradigms and a whole new orientation to health needs and ministries around the world.